丙氟哌酸(Ciprofloxacin,下简称CF)是喹啉羧酸类的新衍生物。体外杀菌试验结果表明,大肠杆菌C_(14)在100%或80%人血清中的生长速率较在50%人血清或肉汤中为低。0.5或0.125μg/ml 浓度的CF 在100%血清中有高度杀菌作用,远较氟哌酸和奥氟哌酸(OF)为强。在80%血清中,1或2μg/ml 浓度的CF 在头2h内对绿脓杆菌的杀菌率为99%,比妥布霉素(4μg/ Ciprofloxacin (Ciprofloxacin, referred to as CF) is a new derivative of quinoline carboxylic acids. In vitro bactericidal test results showed that the growth rate of E. coli C_ (14) in 100% or 80% human serum was lower than in 50% human serum or broth. CF at a concentration of 0.5 or 0.125 μg / ml is highly bactericidal in 100% serum and is far more potent than norfloxacin and norfloxacin (OF). In 80% serum, CF at a concentration of 1 or 2 μg / ml had a bactericidal rate of Pseudomonas aeruginosa of 99% in the first 2 h and was higher than tobramycin (4 μg /