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近年研究证明,维生素D进入人体后,首先必需在肝脏中羟化为25OH维生素D3(25羟维生素D3),然后到肾脏再羟化为1,25二羟维生素D3,才具有调整钙、磷代谢和成骨作用。经绝期后的老年妇女,性激素水平迅速下降。女性激素能使肾脏中的1一羟化酶增加,从而促进1,25二羟维生素D3的生成。女性激素减少,肾脏中的1一羟化酶生
In recent years, studies have shown that vitamin D into the body, the first liver must be hydroxylated to 25OH vitamin D3 (25 hydroxy vitamin D3), and then to the kidney re hydroxylated 1,25 dihydroxy vitamin D3, have to adjust calcium and phosphorus metabolism And osteogenesis. After the older women after the semester, sex hormone levels dropped rapidly. Female hormones can increase 1-hydroxylase in the kidneys, thereby promoting the production of 1,25-dihydroxyvitamin D3. Reduced female hormone, kidney 1 hydroxylase enzyme