冬凌草(Rabdosia rubescens Hemsl)的抗癌有效成分之一冬凌草甲素(Rubescensine A)我们已作了报道。在我们对冬凌草其它二萜成分继续深入研究中,又分得了另一含量较高的、具苦味的二萜成分——冬凌草乙素(Rubescensine B),经结构鉴定与Fujitae从延命草(Isodon japonica Hara)中得到的微量成分Ponicidin为同一化合物;药理研究表明,冬凌草乙素亦具抗肿瘤活性,是冬凌草的另一抗癌有效成分。现将结果报道如下: One of the anticancer active ingredients of Rabdosia rubescens Hemsl, Rubescensine A, has been reported. In our further study of other diterpenoids of Rubescens, we also obtained another high-content, bitter diterpene component, Rubescensine B, which was structurally identified and Fujitae extended its life. The trace compound Ponicidin obtained from grass (Isodon japonica Hara) is the same compound; pharmacological studies have shown that Rubescensin B also has antitumor activity and is another effective anticancer component of Rubescens. The results are reported below: