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以耳廓反射阈、内耳生物电、扫描电镜观察为指标,通过对40只豚鼠的对照试验,观察中药六味地黄汤加味对庆大霉素内耳毒性的预防作用。结果提示六味地黄汤加味能部分减轻庆大霉素对豚鼠内耳听觉和前庭的毒性作用。
The auricular reflex threshold, inner ear bioelectricity, and scanning electron microscopy observations were used as indicators to observe the preventive effects of the Chinese medicine Liuwei Dihuang Decoction on the inner ear toxicity of gentamycin in 40 guinea pigs. The results suggest that Liuwei Dihuang Decoction can partially reduce the toxic effects of gentamicin on auditory and vestibular inner ear of guinea pigs.