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目的:探讨早期康复运动联合血栓通对AMI患者术后康复的疗效及proBNP影响。方法:研究对象为广州市荔湾中医院PCI术后康复患者68例,按随机数字表法分组,各组分别为34例,对照组在PCI术后予以常规治疗,研究组在常规治疗基础上予以早期康复运动联合血栓通治疗,两组共治疗3周为1个疗程,观测临床相应指标,采血测定血清学指标,同时进行随访。结果:相对于治疗前,两组治疗后Fg、vWF、ET-1降低,NO升高,IL-6、CRP、TNF-α及NT-proBNP水平降低,LVEDD、LVESD降低,LVEF、LVFS升高,QOF评分和Barthel评分升高,有差异(P<0.05);相对于对照组,研究组治疗后Fg、vWF、ET-1较低,NO较高,IL-6、CRP、TNF-α及NTproBNP水平较低,LVEDD、LVESD较低,LVEF、LVFS较高,QOF评分和Barthel评分较高,有差异(P<0.05);两组患者均获得随访,无病例脱落现象,两组间心血管事件发生率对比,无差异(P>0.05)。结论:早期康复运动联合血栓通注射液对AMI患者介入术后康复疗效确切,降低proBNP水平,安全性高。
Objective: To investigate the effect of early rehabilitation exercise combined with Xueshuantong on postoperative rehabilitation in patients with AMI and the effect of proBNP. Methods: The object of study was 68 cases of postoperative PCI in Liwan Hospital of Guangzhou, which were divided into three groups by random number table, 34 cases in each group. The control group was treated routinely after PCI. The study group was given on the basis of routine treatment Early rehabilitation exercise combined with Xueshuantong treatment, the two groups were treated for 3 weeks for a course of treatment, the corresponding clinical indicators observed, blood test serological indicators, at the same time for follow-up. Results: The levels of Fg, vWF and ET-1 decreased, the levels of IL-6, CRP, TNF-α and NT-proBNP decreased, LVEDD and LVESD decreased, LVEF and LVFS increased , QOF score and Barthel score (P <0.05). Compared with the control group, the study group had lower Fg, vWF, ET-1, higher NO, IL-6, CRP, NTproBNP level was lower, LVEDD and LVESD were lower, LVEF and LVFS were higher, QOF and Barthel scores were higher (P <0.05); both groups were followed up with no cases of exfoliation, There was no difference in the incidence of events (P> 0.05). Conclusion: Early rehabilitation exercise combined with Xueshuantong injection in patients with AMI after interventional rehabilitation is effective, reduce proBNP levels, high safety.