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丙戊酸(VPA)是一种有效的抗惊厥剂,因有肝毒性反应而使其应用受到限制。曾有二篇报导建议采用VPA的病人若血氨升高,必须减少该药剂量,其他的报导有不同意见。认为高血氨症并没有严重到足够引起症状。
Valproate (VPA) is a potent anticonvulsant that limits its use due to hepatotoxic reactions. There have been two reports suggesting that patients with VPA should reduce the dose of ammonia if their blood ammonia levels rise. Others have different opinions. Hyperhemaminemia is not thought to be serious enough to cause symptoms.