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目的分析2型糖尿病视网膜病变(DR)的危险因素,为DR的防治提供依据。方法同期搜集192例2型糖尿病患者资料,其中伴有DR者87例和不伴有DR的患者(NDR)105例,分析两组患者之间可能诱发或加重DR的相关因素如病程、空腹血糖、餐后2 h血糖、血压、血脂、糖基化血红蛋白、尿白蛋白、总胆固醇等因素与糖尿病DR的相关性。结果通过单因素方差分析发现,糖尿病患者病程、空腹血糖、餐后2 h血糖、糖基化血红蛋白、尿白蛋白、尿肌酐升高与DR的发生呈正相关,血脂、总胆固醇与DR的发病无显著相关性。结论糖尿病DR的发生发展与患者的病程、空腹血糖、餐后2 h血糖、糖基化血红蛋白、血压、尿白蛋白有关,控制上述相关危险因素,有助于防止DR的发生发展。
Objective To analyze the risk factors of type 2 diabetic retinopathy (DR) and provide evidence for the prevention and treatment of DR. Methods A total of 192 patients with type 2 diabetes mellitus were collected during the same period. Among them 87 patients with DR and 105 patients with non-DR were analyzed. The related factors such as duration of disease, fasting blood glucose , Postprandial blood glucose 2 h, blood pressure, blood lipids, glycosylated hemoglobin, urinary albumin, total cholesterol and other factors and diabetes DR. Results One-way analysis of variance showed that the duration of diabetes, fasting blood glucose, postprandial 2h blood glucose, glycosylated hemoglobin, urinary albumin, urinary creatinine were positively correlated with the occurrence of DR. The incidence of blood lipids, total cholesterol and DR were Significant correlation. Conclusions The occurrence and development of diabetes mellitus are related to the patient ’s duration of disease, fasting blood glucose, 2 h postprandial blood glucose, glycosylated hemoglobin, blood pressure and urinary albumin. Controlling the above risk factors may help prevent the occurrence and development of DR.