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应用聚合酶链反应方法，测定２０例急性早幼粒白血病患者的抗调亡基因ｂｃｌ－２ｍＲＮＡ表达水平，并分析基因与急性早幼粒白血病ＰＭＬ－ＲＡＲα融合基因异构体的关系。结果表明，异构体之间的ｂｃｌ－２ｍＲＮＡ表达水平差异无显著性（Ｐ＞０．０５）。提示ＰＭＬ－ＲＡＲα转录本构型不影响临床特征和预后
The expression of anti-apoptotic gene bcl-2 mRNA in 20 patients with acute promyelocytic leukemia was determined by polymerase chain reaction and the relationship between the gene and the isomer of PML-RARα fusion gene in acute promyelocytic leukemia was analyzed. The results showed that there was no significant difference in bcl-2 mRNA expression between isomers (P>0.05). Tips PML-RARα transcript configuration does not affect clinical features and prognosis