论文部分内容阅读
目的比较NSAIDs在糖尿病性白内障患者不同应用时间对术后黄斑中心凹厚度的影响。方法选取2014年6月~2015年6月期间行白内障超声乳化切除联合人工晶体植入术的糖尿病性白内障患者90例。A组30例:术后第1天应用,应用至术后第14天。B组30例:术前2d应用,应用至术后第14天,C组30例:术前2d应用,应用至术后第30天。分别在术前、术后第15天和第30天通过SD-OCT测量黄斑中心凹厚度。结果第15天各组之间黄斑中心凹厚度均没有显著差异,第30天A组、B组之间差异无统计学意义,B组、C组之间差异具有统计学意义(P<0.05)。结论糖尿病性白内障患者术前应用NSAIDs无明显降低黄斑中心凹厚度的增加程度,术后延长使用NSAIDs的时间则可在一定程度上降低黄斑中心凹厚度,从而降低糖尿病患者白内障术后黄斑囊样水肿(CME)发生的风险。
Objective To compare the effect of NSAIDs on the foveal thickness of patients with diabetic cataract at different application time. Methods 90 patients with diabetic cataract who underwent phacoemulsification combined with intraocular lens implantation during June 2014 to June 2015 were selected. A group of 30 patients: the first day after application, applied to the first 14 days after surgery. Group B 30 cases: preoperative 2d application, applied to the first 14 days postoperatively, C group 30 patients: 2d preoperative application, applied to the first 30 days after surgery. The foveal thickness was measured by SD-OCT before surgery, 15 days and 30 days after surgery respectively. Results There was no significant difference in foveal thickness between the groups on the 15th day. There was no significant difference between the A and B groups on the 30th day, and the difference between the B and C groups was statistically significant (P <0.05) . Conclusions The preoperative application of NSAIDs in patients with diabetic cataract did not significantly reduce the increase of foveal thickness, and the prolonged use of NSAIDs could reduce the foveal thickness to a certain extent and thus reduce the macular cystoid edema in patients with diabetic cataract (CME) the risk.