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目的通过对梅毒患者酶联免疫吸附试验(TP-ELISA)、甲苯胺红不加热血清试验(TRUST)、梅毒螺旋体明胶凝集试验(TPPA)检测结果的分析,探讨合适的梅毒检测操作规程,以减少漏检。方法用3种方法同时对184例梅毒患者血清样本进行检测。结果 TP-ELISA法阳性176例、TRUST法阳性146例、TPPA法阳性180例,3种方法检测结果有4种不同的表现模式。结论 TP-ELISA联合TRUST共同进行梅毒筛查能有效减少漏检的发生。检测结果TP-ELISA阳性而TPPA阴性不能排除梅毒螺旋体感染。
Objective To analyze the detection results of TPPA, TPU, TRUST and TPPA in patients with syphilis and explore the appropriate syphilis testing protocol to reduce the risk of syphilis, Missing inspection. Methods Three kinds of methods were used to detect the serum samples of 184 syphilis patients simultaneously. Results There were 176 cases positive for TP-ELISA, 146 cases positive for TRUST and 180 cases positive for TPPA. The results of three methods showed four different expression patterns. Conclusion TP-ELISA combined with TRUST syphilis screening can effectively reduce the missed detection. Test results TP-ELISA positive and TPPA negative can not rule out Treponema pallidum infection.