Biomedical researchers often study binary variables that indicate whether or not a specific event,such as remission of depression symptoms,occurs during the study period.The indicator variable Y takes two values,usually coded as one if the event (remission) is present and zero if the event is not present(non-remission).Let p be the probability that the event occurs ( Y =1),then 1-p will be the probability that the event does not occur ( Y =0).