盗汗,发热和体重减轻是淋巴网细胞瘤的明显症状,提示疾病有广泛播散,尤其有广泛的腹内波及。因此,有这些症状的患者其预后要比没有这些症状的为差,但这些症状的发生机理尚不明了。在发热的本病患者尿中曾发现有致热原,此致热原与多形核粒细胞、单核和巨噬细胞对各种刺激所释放的致热原相似;在实验中,免疫复合物曾证明可以产生致热原,可能由于多形核粒细胞或单核系列细胞固定并吞噬这些复合物所致。作者把18个未经治疗的本病患者,根据AnnArbor分类,分成无症状和有症状两组,各9人;另选12人作为对照组。每人取血后分离血浆,通过葡聚 Night sweats, fever and weight loss are obvious symptoms of lymphoblastoma, suggesting widespread disease, especially in a wide range of intra-abdominal spread. Therefore, patients with these symptoms have worse prognosis than without these symptoms, but the mechanism of these symptoms is not yet known. Pyretic pyrinogen has been found in the urine of patients with fever, which is similar to pyrogen released by various stimuli by polymorphonuclear neutrophils, monocytes and macrophages. In the experiment, the immune complex It has been shown that pyrogen may be produced, possibly due to the immobilization and phagocytosis of these complexes by polymorphonuclear or mononuclear cell lines. The 18 untreated patients were divided into asymptomatic and symptomatic groups according to the Ann Arbor classification, 9 in each; 12 were selected as controls. After each blood plasma separation, through the polyglucosidase