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目的探讨核仁组成区嗜银蛋白（AgNOR）在原发性输尿管癌中的表达方法23例原发性输尿管瘤和9例正常输尿管组织标本进行了AgNOR研究。结果输尿管癌AgNOR计数明显高于正常输尿管组织（p＜0．01），AgNOR计数随着肿瘤病理分级和分期的上升而增加。5年内死于癌转移者，其AgNOR计数明显高于生存5年以上者。结论AgNOR计数在鉴别输尿管良恶性病变和判断预后方面有重要意义。
Objective To investigate the expression of AgNOR in primary ureteral carcinoma of 23 patients with primary ureteral carcinoma and 9 normal ureteral tissues. Results The AgNOR count of ureteral carcinoma was significantly higher than that of normal ureter (p <0.01). The AgNOR count increased with the increase of tumor grade and staging. 5 years died of cancer metastasis, the AgNOR count was significantly higher than those who survived for more than 5 years. Conclusion AgNOR counts have important significance in differentiating benign and malignant ureter and prognosis.