论文部分内容阅读
类风湿关节炎(RA)是一种致残性自身免疫性疾病,如未能及时诊治可出现关节畸形、功能障碍而丧失劳动能力。以往RA的诊断主要依靠临床症状、X线检查以及RF的检测,上述标准的符合者常常已出现关节的损伤,因此临床需要更好的血清学指标,尽早诊断RA。本文比较抗环瓜氨酸肽抗体(抗CCP抗体)、抗角蛋白抗体(AKA)、类风湿因子(RF)、葡萄糖-磷酸异构酶(GPI)和RA33五种相关抗体对RA
Rheumatoid arthritis (RA) is a disabling autoimmune disease, such as the failure to timely diagnosis and treatment of joint deformities, dysfunction and loss of ability to work. In the past, the diagnosis of RA mainly relied on the clinical symptoms, X-ray examination and RF test. The joints of the above-mentioned criteria often had joint injuries. Therefore, the clinical need for better serological markers and early diagnosis of RA. In this paper, five anti-cyclic citrullinated peptide antibodies (anti-CCP), anti-keratin antibodies (AKA), rheumatoid factor (RF), glucose-phosphate isomerase