7432-S是一种新口服头孢菌素类抗菌素,其化学结构如下: 它可杀灭大范围的革兰氏阴性菌和某些革兰氏阳性菌,即使在产β-内酰胺酶的微生物存在时,结构亦很稳定(脆弱拟杆菌除外)。40名健康志愿者随机分组,进行安慰剂对照试验。在单次剂量研究中,分别口服7432-S25,50,100和200mg,血药浓度达峰时间 7432-S is a new oral cephalosporin antibiotic with a chemical structure as follows: It can kill a wide range of Gram-negative bacteria and certain Gram-positive bacteria even in the presence of β-lactamase-producing microorganisms When present, the structure is also very stable (Bacteroides fragilis). Forty healthy volunteers were randomized to placebo-controlled trials. In a single-dose study, oral 7432-S25, 50, 100 and 200 mg, peak plasma concentration time