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目的: 评价经留置导管支气管动脉内交替灌注化疗药物及细胞因子治疗中晚期非小细胞肺癌(NSCLC)的疗效。方法:68 例经病理学证实的NSCLC 患者随机分为A、B 两组,分别进行经留置导管支气管动脉内交替灌注化疗药物及细胞因子和单纯支气管动脉灌注化疗3~4 次。结果:A、B 两组的近期有效率分别为91 .18 % 和44.12 % ,两者具有显著性差异,无严重并发症。结论:留置导管及细胞因子与BAI的有机配合,为中晚期NSCLC 的治疗提供了一条新的有效方法。
OBJECTIVE: To evaluate the efficacy of alternating infusion of chemotherapeutic drugs and cytokines in indwelling catheters for the treatment of advanced non-small cell lung cancer (NSCLC). Methods: Sixty-eight patients with pathologically confirmed NSCLC were randomly divided into two groups: A and B. They were treated with alternating infusion of chemotherapeutic drugs and cytokines and bronchial arterial infusion chemotherapy for 3 to 4 times. Results: The effective rates of A and B in the two groups were 91.18% and 44.12%, respectively. There was significant difference between the two groups and no serious complications. Conclusion: The organic coordination of indwelling catheters and cytokines with BAI provides a new and effective method for the treatment of advanced NSCLC.