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报道国产洛美沙星的临床疗效评价以及体外抗菌活性研究。洛美沙星和氧氟沙星随机对照治疗细菌感染性疾病各１００例，洛美沙星治疗组有效率为９２％，细菌清除率为９３．３％，其临床疗效和细菌清除率与对照药氧氟沙星无显著性差别。洛美沙星开放组治疗细菌感染性疾病２００例，有效率为９３．５％，细菌清除率为９０．１％。体外药敏试验结果显示洛美沙星对Ｇ－菌有较强的体外抗菌活性，对多数肠杆菌科细菌ＭＩＣ９０≤２μｇ／ｍｌ，对Ｇ＋菌亦具有一定的抗菌作用。本品的不良反应发生率为７％。
Reported the clinical efficacy of domestic Lomefloxacin evaluation and in vitro antibacterial activity. Lomefloxacin and Ofloxacin randomized treatment of bacterial infection in 100 cases, lomefloxacin treatment group was 92%, bacterial clearance rate was 93.3%, the clinical efficacy and bacterial clearance rate and the control of oxygen Ofloxacin no significant difference. Lomefloxacin open group treatment of bacterial infections in 200 cases, the effective rate was 93.5%, bacterial clearance rate of 90.1%. In vitro susceptibility test results showed that Lomefloxacin G-bacteria have strong antibacterial activity in vitro, for most Enterobacteriaceae MIC90 ≤ 2μg / ml, also have some antibacterial effect on G + bacteria. This product adverse reaction rate was 7%.