一、CO中毒特点及高压氧治疗机制 CO经呼吸道吸入后,迅速与血液中血红蛋白结合,形成COHb,CO与Hb的结合能力比O_2与Hb的结合能力大250倍,而COHb的解离速度仅为O_2Hb解离速度的1/3600,且COHb的存在还阻碍O_2Hb的解离,这就使Hb严重丧失其携氧功能,造成组织缺氧。CO系原浆毒物,与肌红蛋白结合 First, CO poisoning characteristics and hyperbaric oxygen therapy CO inhalation through the respiratory tract, the rapid binding of hemoglobin in the blood, the formation of COHb, CO and Hb binding capacity O2 and Hb binding capacity of 250 times larger, and COHb dissociation rate only O_2Hb dissociation rate of 1/3600, and the presence of COHb also hinder the dissociation of O_2Hb, which makes the Hb serious loss of its oxygen carrying function, resulting in tissue hypoxia. CO Department virgin poison, and myoglobin binding