对4个饮水型高氟病区居民进行了营养与地方性氟骨症的调查。发现营养状况好的病区患者病情较轻,以早期和硬化型为主。营养状况差的病区患者病情较重,疏松和混合型多见,同时伴有血钙、磷和尿钙降低,血PTH和尿cAMP增高(P<0.05或<0.01)。研究结果提示,由于营养缺乏,特别是钙的摄入不足,可能对氟骨症的发病机制产生明显影响。 The residents of four drinking water-type high-fluoride wards were investigated for nutrition and endemic fluorosis. Found that patients with good nutritional status of patients with mild disease, early and sclerosis-based. Patients with poor nutritional status of patients with severe disease, loose and mixed more common, accompanied by decreased blood calcium, phosphorus and urinary calcium, blood PTH and urine cAMP increased (P <0.05 or <0.01). The results suggest that due to lack of nutrition, especially calcium intake may have a significant impact on the pathogenesis of skeletal fluorosis.