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目的 探讨胞二磷胆碱治疗视神经萎缩的疗效。方法 胞二磷胆碱联合传统疗法治疗视神经萎缩 2 9眼 ,传统疗法治疗视神经萎缩 2 8眼 ,以视力、中心视野及眼电生理 (P -VEP)为观察指标进行比较。结果 胞二磷胆碱联合传统疗法治疗后视力、中心视野、P -VEP (P10 0潜时 )均有好转且在统计学上有非常显著意义 ,而传统疗法仅在中心视野 1项指标上改善有显著意义 ,从总体上看前者的疗效明显优于后者。结论 胞二磷胆碱可有效改善视神经萎缩患者视功能
Objective To investigate the therapeutic effect of citicoline on optic nerve atrophy. Methods 29 patients with optic atrophy were treated with citicoline combined with traditional therapy, and 28 eyes with optic atrophy were treated by traditional therapy. The visual acuity, central visual field and electrophysiology (P-VEP) were compared. Results Both citicoline and traditional therapy had significant improvement in visual acuity, central visual field and P-VEP (P10 latency), but the traditional therapy was only improved in 1 central visual field Significantly, the overall effect of the former is obviously better than the latter. Conclusion Citicoline can effectively improve visual function in patients with optic atrophy