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本文应用RFC—SPA法对临床诊断的42例流行性出血热（EHF）患者外周血抗原及微核进行了检测。抗原阳性率为93％，其对照组抗原检测为阳性，两组比较差异显著（P〈0．01），微核率为5．07‰，其对照组做核率为0．57‰（P〈0．01）。试验组微核率高与抗原阳性率高相符。试验结果表明RFC－SPA抗原检测是简易、早期、快速诊断流行性出血热的可靠方法，可以在基层单位推广。淋巴细胞微核率可作为流行性出血热的早期诊断及病情预测的一项新的辅助指标，抗原及微核检测具有临床应用价值。
In this paper, 42 cases of epidemic hemorrhagic fever (EHF) patients with clinical diagnosis of peripheral blood antigen and micronucleus were detected by RFC-SPA. The antigen positive rate was 93%. The antigen of the control group was positive. The difference between the two groups was significant (P <0.01). The micronucleus rate was 5.07 ‰, and the control group’s nuclear rate was 0.57 ‰ (P <0.01). High micronucleus rate in the experimental group was consistent with the positive rate of antigen. The test results show that RFC-SPA antigen detection is a simple, early, rapid method of reliable diagnosis of epidemic hemorrhagic fever and can be popularized in grassroots units. Lymphocyte micronucleus rate can be used as a new auxiliary indicator of early diagnosis and prognosis of epidemic hemorrhagic fever, and antigen and micronucleus test have clinical value.