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本文选择经胃镜诊断为消化性溃疡活动期的患者１２８例，经锡类散治疗４周后，血浆与胃十二指肠粘膜组织前列腺素Ｅ_２（ＰＧＥ_２）含量明显地高于治疗前，有极显著差异（Ｐ＜０．０ｌ）。治疗后幽门螺旋杆菌（ＨＰ）转阴率为６３．３％，且分布密度减低，与治疗前相比有极显著差异（Ｐ＜０、０１）。因此，锡类散之所以能使溃疡愈合可能与该药促进胃肠粘膜组织合成ＰＧＥ_２增多和抑制ＨＰ的生长、繁殖以致清除有关，而不是由于抑制胃酸分泌和胃泌素释放。
In this paper, 128 patients with active peptic ulcer diagnosed by gastroscopy were selected. After 4 weeks of treatment with tin type powder, prostaglandin E 2 (PGE 2) content in plasma and gastroduodenal mucosal tissue was significantly higher than before treatment. Significant difference (P < 0.01). After treatment, the H. pylori (HP) negative conversion rate was 63.3%, and the distribution density decreased, showing a significant difference compared with before treatment (P<0, 01). Therefore, the reason why tin scattered powder can make ulcer healing may be related to the drug to promote the synthesis of gastrointestinal mucosal tissue increased PGE 2 and inhibition of HP growth, reproduction and removal, but not due to inhibition of gastric acid secretion and gastrin release.