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目的对河北省鼠疫高危地区人群血清鼠疫F1抗体进行延续性调查,进一步了解鼠疫高危地区人群鼠疫感染情况。方法根据康保县、蠡县和张家口市区人口资料,2016年1-6月,选择鼠疫高危地区人群采血分离血清;用IHA、胶体金免疫层析法及ELISA检测鼠疫F1抗体水平。结果采集康保县及蠡县高危人群血清样本7 204份,采用上述3种检测方法,结果均为阴性;100份对照血清用同样方法进行检测,结果也为阴性。2007年在康保县调查时检出阳性4份(4/196)。结论近期在张家口市康保县和保定市蠡县鼠疫高危人群中无鼠疫感染者,即未发生人间鼠疫。
Objective To investigate the epidemiological characteristics of plague in F1 population in high risk areas of plague in Hebei province. Methods According to the population data of Kangbao County, Juxian County and Zhangjiakou City from January to June, 2016, blood samples were collected from the population in high risk area of plague for serum separation. The level of F1 antibody in plague was detected by IHA, colloidal gold immunochromatography and ELISA. Results A total of 7 204 serum samples were collected from high-risk population in Kangbao County and Juxian County. All three samples were negative, and 100 control serum samples were also detected by the same method. The results were also negative. In 2007, four positive samples (4/196) were detected during the investigation in Kangbao County. Conclusion No plague was reported recently in the high-risk groups of the plague in Kangxian County and Baoxian County, Zhangjiakou City.