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膀胱肿瘤浸润性生长以及转移是患者预后不良的主要原因 ,因此了解与膀胱癌浸润与转移的相关因子有重要的临床意义。在诸多影响癌浸润及转移的因素中 ,普遍存在于细胞外基质 (ＥＣＭ )中的透明质酸 (ＨＡ)与癌细胞表面 /内部相应受体的相互作用 ,已引起广泛重视。ＣＤ44基因 ,特
Invasive growth of bladder tumor and metastasis is the main reason for poor prognosis of patients, so to understand the invasion and metastasis of bladder cancer associated factor has important clinical significance. Among many factors influencing cancer invasion and metastasis, the interaction of hyaluronic acid (HA), which is ubiquitous in the extracellular matrix (ECM), with the corresponding receptors on the surface of / on the cancer cells has drawn much attention. CD44 gene, special