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目的探讨食肝口服液时慢性乙肝患者血清戴脂蛋白及中医证型的影响.方法83例慢性乙肝随机分为两组:中药组48例,服用愈肝口服液;西药组35例,静滴强力宁并肌注胸腺肤.其中肝郁脾虚型13例,肝胆温热型10例,脾肾阳虚型8例,瘀血阻络型8例.肝肾阴虚型9例。免疫散射比浊法测apoA;和apoB.结果愈肝口服液能够升高慢性乙肝患者血清apoA,和apoB胆固醇、高密度脂蛋白水平,(P<0.05~0,01),对apoA;和apoB的比值具有改善作用(P<0.05);中医辨证以肝郁脾虚型、肝胆湿热型、肝肾阳虚型疗效较好.结论意肝口服液对慢性乙肝患者血清apoA;和apoB水平具有调节作用。
Objective To explore the effect of the serum lipoprotein and TCM syndrome of Chronic Hepatitis B patients treated with Hugan oral liquid. Methods 83 cases of chronic hepatitis B were randomly divided into two groups: 48 cases of Chinese medicine group, taking the liver liquid; 35 cases of Western medicine group, intravenous injection of strong and intramuscular injection of thymus skin. Among them, there were 13 cases of liver depression and spleen deficiency, 10 cases of hepatobiliary warm type, 8 cases of spleen and kidney yang deficiency, 8 cases of blood stasis blocking type. Yin and kidney in 9 cases. Immuno-nephelometry was used to measure apoA; and apoB. Results Yugan decoction could increase serum apoA and apoB cholesterol and high density lipoprotein levels in patients with chronic hepatitis B (P <0.05-0.01), and ameliorate the ratio of apoA and apoB (P0.01) .05); TCM differentiation of liver spleen type, liver and gallbladder dampness type, liver and yang type is better. Conclusion YiGan Oral Liquid can regulate the level of serum apoA and apoB in chronic hepatitis B patients.