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目的:报道1例体外受精/单精子胞浆内注射-胚胎移植(IVF/ICSI-ET)后单绒毛膜四胎合并单绒毛膜单胎妊娠。方法:患者为26岁女性,接受IVF/ICSI-ET治疗,取卵后3d移植2枚8-细胞胚胎。结果:孕6周经阴道B超示单绒毛膜四胎合并单绒毛膜单胎妊娠。选择性减胎术在孕7周进行,减灭单绒毛膜四胎。孕40周行剖宫产术娩出单活男婴。结论:高龄、透明带操作、胚胎培养时间和条件、促排卵治疗等多种因素可造成单卵多胎妊娠。选择性减胎术可降低多胎妊娠的不利影响,但应更注重预防其发生。
OBJECTIVE: To report single-chorionic, single-fetus, single-chorionic singleton pregnancy in IVF / ICSI-ET after in vitro fertilization / single sperm cytoplasmic injection-embryo transfer. Methods: The patients were 26-year-old women receiving IVF / ICSI-ET treatment. Three 8-cell embryos were transplanted 3 days after ovulation. Results: 6 weeks pregnant transvaginal B-ultrasound showed a single chorion with four single-chorionic singleton pregnancy. Optional abortion surgery in the first 7 weeks of pregnancy, abortion minus single chorionic four. 40 weeks pregnant cesarean delivery of single live baby boy. CONCLUSION: Many factors such as advanced age, operation of zona pellucida, time and condition of embryo culture, ovulation induction therapy and so on can result in monozygotic multiple pregnancy. Optional abortion can reduce the adverse effects of multiple pregnancy, but should pay more attention to prevent its occurrence.