大鼠经多氯联苯处理后,分离肝微粒体的六种P450亚型,分别与NADPH-细胞色素P450还原酶和十二桂酰卵磷脂重组,形成六种P450酶系,即P450重组酶系A_1、A_2、B. C_1、C_2和D。这六种重组酶系对37种外来化合物的催化速率不同,其中以C_1和C_2酶系催化活力最强,其次为A_1酶系,B After treatment with PCBs, the six P450 subtypes of liver microsomes were isolated and recombined with NADPH-cytochrome P450 reductase and dodecyl-lecithin to form six P450 enzymes, namely P450 recombinase Department A_1, A_2, B. C_1, C_2 and D. The catalytic rates of these six recombinant enzymes to 37 foreign compounds were different, among which C 1 and C 2 enzymes had the highest catalytic activity, followed by A 1, B