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已发现去甲肾上腺素摄取异常可反映成年心衰患者心脏神经元肾上腺素能功能的损伤 ,但尚无儿童期扩张型心肌病(DCM)方面的报道。此研究目的是以 1 2 3I-间碘苄胍 (MIBG)显像法估价特发性 DCM儿童心脏神经元的功能。1996年 10月至 1998年 6月间 2 6例 (平均年龄为 44± 5 0个月 )
Abnormalities in norepinephrine uptake have been found to reflect adrenergic impairment of cardiac neurons in adult patients with heart failure, but there are no reports of DCM in childhood. The purpose of this study was to evaluate the function of cardiac neurons in children with idiopathic DCM using 123I-MIBG imaging. Between October 1996 and June 1998, 26 patients (mean age 44 ± 50 months)