大量的体内和体外实验研究证明，由ＳｉＯ２粉尘诱导的肺泡巨噬细胞（ＰＡＭ）膜和肺组织的脂质过氧化反应是导致肺泡巨噬细胞损伤和肺组织纤维化病变的主要原因［１］。本实验对实验性矽肺大鼠体内脂质过氧化与抗氧化的水平进行了研究。１材料与方法１．１实验动物与分组... A large number of in vivo and in vitro studies have demonstrated that the lipid peroxidation induced by SiO2 dust in alveolar macrophages (PAM) and lung tissue is the major cause of alveolar macrophage injury and lung fibrosis [1] . In this experiment, the level of lipid peroxidation and anti-oxidation in experimental silicosis rats were studied. 1 Materials and Methods 1.1 Experimental animals and groups ...