论文部分内容阅读
经酶联免疫吸附试验（ＥＬＩＳＡ）检测３１例散发性脑炎患儿血清和脑脊液（ＣＳＦ）中的单纯疱疹病毒Ⅰ、Ⅱ型（ＨＳＶ－Ｉ，ＨＳＶ－Ⅱ）ＩｇＭ、ＩｇＧ抗体；用聚合酶链反应（ＰＣＲ）检测ＣＳＦ中ＨＳＶ－ＤＮＡ。结果１５例确诊为单纯疤疹脑炎（ＨＳＥ），１６例为非单纯疱疹脑炎（ＮＨＳＳＥ）。在ＨＳＥ的临床表现中，意识障碍发生率显著高于ＮＨＳＳＥ；实验室脑脊液常规检测，ＨＳＥ多见红细胞；脑电图及ＣＴ检查额，颞部位有特征性改变。提示ＨＳＥ的病原学诊断对于早期诊断及指导临床治疗具有重要意义．
The herpes simplex virus type I and type II (HSV-I, HSV-II) IgM and IgG antibodies in serum and cerebrospinal fluid (CSF) of 31 children with sporadic encephalitis were detected by enzyme linked immunosorbent assay (ELISA) Chain reaction (PCR) to detect CSF HSV-DNA. Results Fifteen patients were diagnosed as herpes simplex encephalitis (HSE) and 16 as non-herpes simplex encephalitis (NHSSE). In the clinical manifestations of HSE, the incidence of disturbance of consciousness was significantly higher than that of NHSSE. Conventional testing of cerebrospinal fluid in laboratory, more common HSE erythrocytes; EEG and CT examination of the amount of characteristic changes in the temporal region. Tip HSE etiological diagnosis for early diagnosis and guidance of clinical treatment is of great significance.