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目的:了解不同年龄、性别、季节等因素对疫苗接种免疫效果的影响,为狂犬病的防治提供指导。方法:采用ELISA方法对2006年1月至2008年12月被猫犬抓(咬)伤且全程足量注射狂犬疫苗者7045例进行抗体检测及分析。结果:7045例观察对象抗体平均阳性率为95.3%。各年龄段的血清抗体水平不同,季节和性别对抗体水平无明显影响。结论:受动物致伤后要及时全程注射狂犬疫苗,免疫后检测血清抗体水平十分重要,对暂未产生抗体者要及时加强免疫,确保免疫效果。
Objective: To understand the effects of different age, sex, season and other factors on the immunization effect of vaccination and provide guidance for the prevention and treatment of rabies. Methods: ELISA was used to detect and analyze 7045 cases of rabies vaccine caught and bitten by dogs and cats from January 2006 to December 2008. Results: The average positive rate of antibody in 7045 cases was 95.3%. Serum antibody levels vary by age, but seasons and gender have no significant effect on antibody levels. Conclusion: It is very important to detect rabies vaccine in rabbits after the animal is injured. It is very important to detect serum antibody level after immunization. In the case of antibodies not yet produced, the immunity should be strengthened to ensure the immune effect.