选择180例伴有游走性红斑的莱姆病病人作为研究对象,随机分为3组,分别单纯口服多西环素10日、口服多西环素10日加单剂静脉滴注头孢曲松或口服多西环素20日。开始治疗后20日、3个月、12个月和30个月分别对疗效进行评估,基于观察和神经认知试验对临床转归进行评价。结果显示,在所 180 cases of lyme disease accompanied by migratory erythema were selected as study subjects and were randomly divided into 3 groups: oral administration of doxycycline 10 days alone, oral administration of doxycycline 10 days plus a single intravenous infusion of ceftriaxone Or oral doxycycline on the 20th. Efficacy was assessed at 20, 3, 12 and 30 months after initiation of treatment, and clinical outcomes were evaluated based on observations and neurocognitive tests. The results show that in the