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长期透析可使组织淀粉样变性,并发腕管综合征(CTS),以往治疗CTS主要方法是外科腕管切开术,或透析中清除血中β_2-微球蛋白(β_2-microglobulin)。但因类淀粉物的全身沉积,外科疗法及血透效果常不十分满意。作者用大剂量的千金藤素治疗7例,有较好效果。年龄42～69岁,男1例,女6例。原发病:慢性肾炎、肾盂肾炎3例,妊娠中毒症2例,糖尿病肾病及范可尼综合征各1例。合并铝中毒3例,甲状旁腺功能亢进2例,风湿性关节炎1例。透析时间8年8月～17年8个月。 CTS主要表现:1～3指及腕部肿胀、疼痛,麻木,鱼际萎缩。用药方法:千金藤素散剂一日60mg,分三次饭后口服,无效时剂量增加至一日120mg,仍无效者停止服药。结果:指腕麻木5例缓解(71%),4例指肿胀2例缓
Long-term dialysis can make tissue amyloidosis, complicated with carpal tunnel syndrome (CTS), the main method of treatment of CTS in the past is surgical carpal tunneling, or dialysis to remove blood β_2-microglobulin (β_2-microglobulin). However, due to the deposition of amyloid whole body, surgical treatment and hemodialysis effects are often not very satisfied. The authors treated with large doses of cortisone 7 cases, with good results. Aged 42 to 69 years old, 1 males and 6 females. Primary disease: chronic nephritis, pyelonephritis in 3 cases, pregnancy poisoning in 2 cases, diabetic nephropathy and Fanconi syndrome in 1 case. Aluminum poisoning in 3 cases, hyperparathyroidism in 2 cases, 1 case of rheumatoid arthritis. Dialysis time 8 years from August to 17 years and 8 months. CTS main performance: 1 ~ 3 fingers and wrist swelling, pain, numbness, atrophy. Medication Methods: Cendobanil powder 60mg a day, three times after oral administration, the dose was increased to 120mg on the 1st, still ineffective to stop taking medication. Results: 5 cases of wrist numbness relief (71%), 4 cases of swelling refers to 2 cases of slow