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目的探讨早产儿血小板参数的动态变化及其与早产儿并发症的关系。方法对96例早产儿于出生24h内和生后1周进行血小板参数检测。结果早产儿胎龄越小、出生体重越低,出生24h内PLT越低、MPV和PDW越大。无窒息及无并发症早产儿PLT、MPV及PDW生后1周较出生24h内有不同程度升高(P<0.05或0·01)。出生24h内,IVH和RDS组PLT明显低于无并发症组(P<0.01和0·05),IVH组MPV明显大于无并发症组(P<0.01);生后1周,窒息组PLT明显低于无窒息组(P<0.01),MPV、PDW明显大于无窒息组(P<0.01和0·05),低体温和感染组PLT明显低于无并发症组(P<0.05和0·01),感染组MPV明显大于无并发症组(P<0.05)。结论早产儿血小板参数与胎龄、出生体重及日龄有关;出生时合并窒息及早产儿并发症与血小板参数密切相关。
Objective To investigate the dynamic changes of platelet parameters in preterm infants and its relationship with the complications of premature infants. Methods Ninety-six preterm infants were tested for platelet parameters within 24h after birth and one week after birth. Results The smaller the gestational age, the lower the birth weight, the lower the PLT within 24 hours of birth and the greater the MPV and PDW. PLT, MPV and PDW in preterm infants without asphyxia and without complications were increased to some extent within one week after birth (P <0.05 or 0.01). Within 24 hours after birth, PLT in IVH and RDS group was significantly lower than that in non-complication group (P <0.01 and 0.05), MPV in IVH group was significantly higher than that in non-complication group (P <0.01) (P <0.01 and 0.05). The PLT in hypothermia and infection group was significantly lower than that in non-complication group (P <0.05 and 0.01) ), MPV infection group was significantly greater than the non-complication group (P <0.05). Conclusion The platelet parameters in preterm infants are related to gestational age, birth weight and age. The complications of birth asphyxia and premature infants are closely related to platelet parameters.