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用辐射热甩尾反射测定大鼠痛阈的方法，观察并比较了东亚钳蝎毒素和吗啡的镇痛作用。结果表明：向侧脑室内注射２μＬ或肌肉注射０．０５μＬ、０．０１％蝎毒液的镇痛作用分别比相同给药途径、同浓度、同剂量吗啡的镇痛作用强，二者差异非常显著，Ｐ＜０．０ｌ。侧脑室内注射０．０３％蝎毒液２μＬ的镇痛作用比同浓度、同剂量吗啡的镇痛作用梢强，但无显著差异，Ｐ＞０．０５。蝎毒经肌肉注射后在较短的时间内即可使大鼠痛阈明显升高。证明蝎毒可通过血脑屏障进入中枢神经系统，产生镇痛作用。
The pain threshold of rats was measured by radiant heat tail-scattering reflex, and the analgesic effect of carrageenan and morphine was observed and compared. The results showed that the analgesic effect of intracerebroventricular injection of 2μL or intramuscular injection of 0.05μL and 0.01% sputum venom was stronger than that of the same route of administration, the same concentration, and the same dose of morphine, and the difference was significant. ,P<0.0l. The analgesic effect of intracerebroventricular injection of 0.03% scorpion venom 2μL was stronger than that of the same dose and the same dose of morphine, but there was no significant difference, P>0.05. The musculoskeletal poisoning can increase the pain threshold in rats in a short period of time after intramuscular injection. It is proved that scorpion venom enters the central nervous system through the blood-brain barrier and produces analgesia.