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为了观察美蓝对内毒素性休克血压的影响，作者通过动物实验后发现，对照组大白兔静注生理盐水前后，平均动脉压、血浆环磷酸鸟着、心钠素均无差异（P＞0．05）；而实验组休克大白兔经静注美蓝前后比较，平均动脉压升高（P＜0．01），血浆环磷酸写音（P＜0.05）；并且实验组与对照组相比较，平均动脉压和血浆环磷酸鸟着水平亦有显著差异（P＜0．01）。提示血浆环磷酸鸟普值升高与内毒素性休克时的低血压、低循环阻力有关，提示美蓝的应用可有效地抑制体内可溶性鸟音酸环化酶，使休克的大白兔血浆环磷酸鸟着值下降，血压上升，并具有桔抗一氧化氮的作用，结果提示美蓝有可能作为感染性休克的治疗药物。
In order to observe the effect of methylene blue on endotoxic shock blood pressure, the authors found that there was no difference in average arterial pressure, plasma CPP, atrial natriuretic peptide and atrial natriuretic peptide before and after intravenous injection of saline (P <0.05). Compared with the control group, the mean arterial blood pressure (P <0.01) of the rabbits in experimental group were significantly higher than those in the control group , Mean arterial pressure and plasma levels of cyclophosphamide were also significantly different (P <0.01). Suggesting that elevated plasma CPP value is associated with hypotension and low circulating resistance during endotoxic shock, suggesting that the application of methylene blue may effectively inhibit the release of soluble avian acid cyclase in rabbits, Bird decline in value, blood pressure, and orange with anti-nitric oxide effect, the results suggest that methylene blue may be used as a septic shock treatment drugs.