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目的 观察思美泰治疗急慢性乙型肝炎引起的老年肝内胆汁淤积症的疗效。方法 将 6 2例 6 0岁以上的肝内胆汁淤积症患者分成治疗组和对照组。治疗组 32例用思美泰注射液 1g ,对照组 30例用茵桅黄注射液 30ml,分别加入 5 %葡萄糖注射液 2 5 0ml,静滴 ,每日 1次 ,连用 5周。治疗前后检测肝功能各项指标 ,并观察临床症状变化及副作用。结果 两组对比观察 ,临床症状的改善及肝功能指标的复常率 ,治疗组均优于对照组。两组相比 ,差异有显著性 (P <0 .0 5 )。结论 思美泰是治疗老年肝内胆汁淤积症的首选有效药物。
Objective To observe the effect of Simmel in the treatment of senile chronic intrahepatic cholestasis caused by acute and chronic hepatitis B Methods Sixty-two patients with intrahepatic cholestasis over 60 years old were divided into treatment group and control group. The treatment group, 32 cases of Smectite injection 1g, 30 cases of the control group with Yin Mao Huang injection 30ml, were added 5% glucose injection 250ml, intravenously, once daily for 5 weeks. Before and after treatment to detect various indicators of liver function, and observe the clinical symptoms and side effects. Results The two groups were compared, the improvement of clinical symptoms and the rate of normalization of liver function index, the treatment group were better than the control group. There was significant difference between the two groups (P <0.05). Conclusion Simei Tai is the first choice of effective drugs for the treatment of intrahepatic cholestasis in the elderly.