报告1例男5岁白人新生儿红斑狼疮(NLE)患儿,出生时有泛发环状红斑和散在毛细血管扩张,血小板明显减少(24×10~9/L)、ANA阳性(IgG滴度1:256)、抗Ro及抗La抗体亦为阳性,其母亦有相同类型的抗体。环状皮损病理显示表皮基底层广泛空泡变性,真皮上部淋巴细胞浸润,免疫荧光检 Reported a case of male 5-year-old white newborn lupus erythematosus (NLE), children with generalized erythema and diffuse telangiectasia at birth, significantly reduced platelet (24 × 10 ~ 9 / L), ANA positive 1: 256), anti-Ro and anti-La antibodies are also positive, the mother also has the same type of antibody. Cyclical lesions showed extensive vacuolar degeneration of the basal layer of the epidermis, infiltration of dermal lymphocytes, immunofluorescence