血清胆酸显著升高是妊娠肝内胆汁郁积症的一项特征性指标。应用放免分析法测定47例患者的血清结合胆酸,平均20.58±11.32μmol/L,较对照组增加8.3～144.8倍。按胆酸低、中、高分为三组,分别与临床症状、肝功能、分娩方式和妊娠结局进行比较,发现高胆酸组病情重、发病早和分娩并发症多。说明测定血清胆酸对诊断本病、判断病情及预后和及时处理具有重要的参考价值。 Significant increase in serum bile acid is a characteristic indicator of intrahepatic cholestasis of pregnancy. 47 patients with serum bile acids were measured by radioimmunoassay, with an average of 20.58 ± 11.32μmol / L, which was 8.3 ~ 144.8 times more than that of the control group. By bile acid low, medium and high scores were divided into three groups, respectively, clinical symptoms, liver function, mode of delivery and pregnancy outcomes were compared and found that patients with severe bile acid group of severe illness, early onset and complications of childbirth. Description Determination of serum bile acid diagnosis of the disease, to determine the condition and prognosis and timely treatment of important reference value.