黑色素斑—胃肠道息肉病(Peutz-Jegher氏综合征),属于少见疾病。自1921年荷兰学者Peutz氏报告了第一例后,至今报告病例为数不多。现报告1例如下: 患者女,25岁,农民。3～4岁时发现口唇黑色素斑点,以后渐增多,口周围,口腔粘膜以及手掌、足底亦出现黑色素斑点。近20天来(月经后)脐周疼痛,肛门坠胀感,伴黑便。于1986年7月8日就诊入院。患者否认有家族史。 Melanoma - gastrointestinal polyposis (Peutz-Jegher’s syndrome), is a rare disease. Since the first case was reported by the Dutch scholar Peutz in 1921, few cases have been reported to date. Now report a case as follows: Female patient, 25 years old, farmer. 3 to 4 years old found that lips melanin spots, after gradually increased, around the mouth, oral mucosa and palms, also appeared melatonin spots. Nearly 20 days to (after menstruation) Cullen pain, anal bulge, with melena. On July 8, 1986 visit to hospital. Patients denied having a family history.