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目的对１８ＦＦＤＧＰＥＴ在中枢神经系统疾病临床诊断中应用的初步体会作一介绍。方法１８ＦＦＤＧＰＥＴ检查共计１７例，所有患者静脉注射１８Ｆ脱氧葡萄糖（ＦＤＧ）１０ｍＣｉ后４０分钟进行脑１８ＦＦＤＧ正电子发射断层显像（ＰＥＴ），其结果与同期的ＣＴ、ＭＲＩ、ＥＥＧ结果进行比较。结果在１０例癫痫发作间歇期病人中，４０％的病例１８ＦＦＤＧＰＥＴ显示病侧局部脑叶葡萄糖代谢即ＦＤＧ摄取低下（较正常健侧皮层放射性计数降低２０％以上），５０％的病例脑叶葡萄糖代谢正常；脑梗塞、脑外伤后软化灶１８ＦＦＤＧＰＥＴ均显示为局部脑叶葡萄糖代谢明显下降或缺损，其余多发性硬化、多发小脓肿、蛛网膜囊肿均表现为脑内葡萄糖代谢正常。结论初步的临床应用显示，１８ＦＦＤＧＰＥＴ在中枢神经系统疾病诊断中具有重要的临床价值
Objective To introduce 18F FDGET in the clinical diagnosis of central nervous system diseases. Methods A total of 17 patients underwent 18F-FDG PET examinations. All patients underwent 18F-FDG positron emission tomography (PET) 40 minutes after intravenous injection of 18F-FDG 10mCi. The results were in good agreement with those of CT, MRI and EEG Compare. Results Of the 10 patients with interictal seizures, 18F-FDG PETET showed that 40% of patients had local lobular glucose metabolism, ie, low FDG uptake (more than 20% decrease in normal contralateral cortical radioactivity), 50% of cases Normal glucose metabolism; cerebral infarction, traumatic brain injury after 18F FDGET showed a significant loss or defect of local cerebral glucose metabolism, and the remaining multiple sclerosis, multiple small abscess, arachnoid cysts are manifested as normal brain glucose metabolism. Conclusion The preliminary clinical application shows that 18F FDG PETET has important clinical value in the diagnosis of central nervous system diseases