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目的 :研究康艾注射液联合化疗在治疗胃癌方面的临床疗效。方法 :选取我院自2012年1月—2013年1月,住院部所收治的胃癌患者共计80例为研究对象。按照数字随机表方式,随机划分为治疗组、对照组,每组患者各计40例。治疗组患者给予康艾注射液联合化疗的治疗方案,对照组患者给予常规化疗治疗方案。对两组患者在接受治疗30 d后的临床疗效,包括治疗有效率、体力状况评分、胃肠道反应分级,进行综合对比与分析。结果 :通过30 d的临床治疗,从治疗有效率方面来说,治疗组总有效率为62.50%(25/40),对照组总有效率为40.00%(16/40),治疗组明显高于对照组;从体力状况评分方面来说,治疗组评分改善率为82.50%(33/40),对照组评分改善率为37.50%(15/40),治疗组明显高于对照组;从胃肠道反应分级方面来说,治疗组Ⅰ度及以下消化道反应率为87.50%(35/40),对照组Ⅰ度及以下消化道反应率为62.50%(25/40),治疗组明显高于对照组;上述数据期间比较差异显著(P<0.05),具有统计学意义。结论 :康艾注射液联合化疗治疗胃癌具有疗效确切的优势,可改善患者体力状态,减轻胃肠道相关毒副反应,值得临床进一步应用。
Objective: To study the clinical efficacy of Kangai injection combined with chemotherapy in the treatment of gastric cancer. Methods: A total of 80 patients with gastric cancer admitted to our hospital from January 2012 to January 2013 were enrolled in this study. According to the digital random table method, randomly divided into treatment group, control group, each group of 40 patients in each. Patients in the treatment group were treated with Kang Ai injection combined with chemotherapy, while patients in the control group were given conventional chemotherapy. The clinical efficacy of the two groups of patients after 30 days of treatment, including the treatment efficiency, physical status score, gastrointestinal reaction grade, comprehensive comparison and analysis. Results: After 30 days of treatment, the total effective rate was 62.50% (25/40) in the treatment group and 40.00% (16/40) in the control group, which was significantly higher than that in the treatment group The improvement rate of the treatment group was 82.50% (33/40) and that of the control group was 37.50% (15/40), and the treatment group was significantly higher than that of the control group In terms of the grade of reaction, the response rate of Ⅰ and below in the treatment group was 87.50% (35/40), while the control group Ⅰ and below gastrointestinal response rate was 62.50% (25/40), the treatment group was significantly higher than Control group; the above data were significantly different (P <0.05), with statistical significance. Conclusion: Kangai injection combined with chemotherapy for gastric cancer has definite curative effect, which can improve the physical status of patients and reduce the gastrointestinal related toxic and side effects, which is worth further clinical application.