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采用酶联免疫法(ELISA)测定32例动脉粥样硬化性脑梗塞患者和31例正常人的血浆氧化修饰低密度脂蛋白(OXLDL)和脂蛋白(a)〔Lp(a)〕含量。结果表明,脑梗塞患者血浆中OXLDL和Lp(a)含量明显高于对照组,有显著差异(P<0.01)。OXLDL与Lp(a)含量之间无显著相关性(P>0.05)。提示OXLDL、Lp(a)是两种相互独立的脂蛋白,在动脉粥样硬化性脑梗塞的发生和发展中具有重要作用。
The levels of plasma oxidized low density lipoprotein (OXLDL) and lipoprotein (a) [Lp (a)] in 32 patients with atherosclerotic cerebral infarction and 31 healthy controls were measured by enzyme linked immunosorbent assay (ELISA). The results showed that the plasma levels of OXLDL and Lp (a) in patients with cerebral infarction were significantly higher than those in the control group (P <0.01). There was no significant correlation between OXLDL and Lp (a) content (P> 0.05). It is suggested that OXLDL and Lp (a) are two independent lipoproteins and play an important role in the development and progression of atherosclerotic cerebral infarction.