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目的研究脑出血并发高钠血症病人病死率及其发生原因。方法收集 2 2 1例脑出血病人 ,其中 33例并发高钠血症 (血清钠离子浓度 >145mmol/L)者作为高钠血症组 (A组 ) ,其余 188例不伴高钠血症者归入对照组 (B组 )。结果A组死亡 18例 ,病死率 5 4 5 5 % ;B组死亡 43例 ,病死率 2 2 87% ,两者差异有显著意义 (P <0 0 1)。既往有糖尿病病史者百分比 ,A组明显高于B组 (P <0 0 1)。丘脑出血发生率 ,A组明显高于B组 (P <0 0 1)。体温超过 39℃者百分比 ,A组明显高于B组 (P <0 0 1)。甘露醇每日用量大于 5 0 0ml持续 10日以上者百分比 ,A组明显高于B组 (0 0 5 >P >0 0 1)。结论脑出血并发高钠血症者 ,其病死率明显高于对照组 ,且血清钠离子水平越高病死率越高 ,其发生原因与糖尿病、丘脑出血、发热、甘露醇使用量大等因素相关。
Objective To study the mortality of patients with cerebral hemorrhage complicated with hypernatremia and its causes. Methods A total of 221 patients with cerebral hemorrhage were collected. Among them, 33 were hypernatremia (serum sodium concentration> 145mmol / L) as hypernatremia group (A), and the remaining 188 patients without hypernatremia Into the control group (B group). Results There were 18 deaths in group A with a mortality rate of 54.55%. There were 43 deaths in group B with a mortality of 22 87%. There was significant difference between the two groups (P <0.01). The percentage of previous history of diabetes mellitus was significantly higher in group A than in group B (P <0.01). The incidence of thalamic hemorrhage in group A was significantly higher than that in group B (P <0.01). Body temperature over 39% of the percentage, A group was significantly higher than the B group (P <0 0 1). Mannitol daily consumption of more than 500 ml for more than 10 days percentage, A group was significantly higher than the B group (0 0 5> P> 0 0 1). Conclusions The mortality of patients with cerebral hemorrhage complicated by hypernatremia is significantly higher than that of the control group, and the higher the serum sodium level is, the higher the mortality is. The causes are related to the factors such as diabetes, thalamic hemorrhage, fever and mannitol consumption .