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本文报告原发性肾病综合征50例,Ⅰ型40例,Ⅱ型10例。全部病例均经肾活检确定病理类型,其中系膜增殖性肾炎17例(34％),膜增殖性肾炎12例(24％),毛细血管内膜增殖性肾炎9例(18％),膜性肾病及微小病变性肾病各3例(6％),局灶硬化性肾炎6例(12％)。经“三联疗法”治疗4～6周后,蛋白尿消失者22例,显效率44％,总有效率达94％。除局灶硬化性肾炎外,其余各类型肾炎均取得显著疗效。可能与各类型肾脏疾病免疫损伤程度有关。
This article reports 50 cases of primary nephrotic syndrome, type Ⅰ 40 cases, type Ⅱ 10 cases. All cases were confirmed by pathological renal biopsy, including 17 cases of mesangial proliferative glomerulonephritis (34%), 12 cases of proliferative glomerulonephritis (24%), 9 cases of capillary intimal proliferative glomerulonephritis (18%), Nephropathy and minimal nephropathy in 3 cases (6%), focal sclerosing nephritis in 6 cases (12%). After “triple therapy” treatment of 4 to 6 weeks, 22 cases of proteinuria disappeared, markedly effective rate of 44%, the total effective rate of 94%. In addition to focal sclerosing nephritis, the remaining types of nephritis have achieved significant results. May be related to the degree of various types of kidney disease immune damage.