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目的探讨胆道支架植入术联合三维适形放疗对恶性梗阻性黄疸的临床疗效,评价其应用价值。方法15例失去手术机会的恶性梗阻性黄疸患者放置胆道支架后接受肿瘤局部三维适形放疗。结果治疗后所有患者黄疸、临床症状均明显缓解,同时取得8例PR、5例SD的近期肿瘤控制率,并发症主要为肝区疼痛,经对症处理症状缓解,未见严重并发症发生。结论初步观察表明胆道支架置入治疗恶性梗阻性黄疸具有微创、有效的优点,而适形放疗可减少支架置入后再狭窄阻塞的可能的特点,是一种安全可行的方法。
Objective To investigate the clinical effect of biliary stenting combined with three-dimensional conformal radiotherapy on malignant obstructive jaundice and evaluate its application value. Methods Fifteen patients with malignant obstructive jaundice who had lost the chance of surgery underwent local three-dimensional conformal radiotherapy of the tumor after placing the biliary stent. Results After treatment, all patients had obvious symptoms of jaundice and clinical symptoms. At the same time, 8 cases of PR and 5 cases of SD were treated with advanced tumor control. The main complication was liver pain. Symptomatic treatment was relieved without serious complications. Conclusions Preliminary observation shows that the biliary stenting has the advantage of minimally invasive and effective in treating malignant obstructive jaundice, and the conformal radiotherapy can reduce the possible restenosis and occlusion characteristics after stenting, which is a safe and feasible method.