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探讨一氧化氮 (NO)及腺苷脱氨酶 (ADA)在结核性及癌性胸腔积液中含量变化的意义。方法 :结核性及癌性胸腔积液各 2 0例 ,参照Rochett和Green的方法测定胸腔积液中NO2 -/NO3 -以反映NO水平 ,采用改进的杨氏法测定胸腔积液中ADA含量。结果 :结核性胸腔积液及癌性胸腔积液NO水平增高 ,但二者无显著性差异 (P >0 .0 5 ) ,结核性胸腔积液ADA明显高于癌性胸腔积液 ,二者有显著性差异 (P <0 .0 0 1)。结论 :提示结核性和癌性胸腔积液中均有内源性NO产生 ,NO及ADA水平的变化 ,可作为胸腔积液诊断与鉴别诊断的一项辅助检查指标
To investigate the significance of nitric oxide (NO) and adenosine deaminase (ADA) in tuberculous and cancerous pleural effusion. Methods: Twenty cases of tuberculous and cancerous pleural effusion were collected. The levels of NO2 - / NO3 - in the pleural effusion were determined by the method of Rochett and Green. The levels of ADA in pleural effusion were measured by the modified Young’s method. Results: The levels of NO in tuberculous pleural effusion and cancerous pleural effusion increased, but there was no significant difference between the two (P> 0.05). ADA in tuberculous pleural effusion was significantly higher than that in cancerous pleural effusion, both There was a significant difference (P <0. 0 0 1). CONCLUSION: It is suggested that both endogenous NO production and NO and ADA levels in both tuberculous and cancerous pleural effusions may be used as an auxiliary test for the diagnosis and differential diagnosis of pleural effusion