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为防止胃肠道癌术后腹腔内复发和肝转移,探讨切实有效的辅助治疗措施。对50例胃肠道癌根治术后行卡铂、5-Fu、IL-2腹腔内灌注,与50例根治术后单用静脉化疗相比较。腹腔化疗组5年复发率(32%)明显低于静脉化疗组(62%);5年生存率(72%)明显高于静脉化疗组(44%)。腹腔化疗组全身毒副反应明显低于静脉化疗组。腹腔热灌注化疗对胃肠道癌术后腹腔内复发及肝转移的预防和治疗颇有意义
In order to prevent postoperative intra-abdominal recurrence and liver metastasis of gastrointestinal cancer, effective and effective supplementary treatment measures were explored. Peritoneal perfusion of carboplatin, 5-Fu, and IL-2 was performed on 50 patients with gastrointestinal cancer after radical resection and compared with 50 patients who received single-use intravenous chemotherapy after radical resection. The 5-year recurrence rate in the intraperitoneal chemotherapy group (32%) was significantly lower than that in the intravenous chemotherapy group (62%); the 5-year survival rate (72%) was significantly higher than that in the intravenous chemotherapy group (44%). The systemic toxicity of the intraperitoneal chemotherapy group was significantly lower than that of the intravenous chemotherapy group. Peritoneal hyperthermic perfusion chemotherapy is of great significance in the prevention and treatment of intra-abdominal recurrence and liver metastasis after gastrointestinal cancer surgery