基因治疗已与手术、化疗、放疗共同构成当前肿瘤治疗四大支柱。从分子水平看、肿瘤病因主要有癌基因激活和抑癌基因突变失活、细胞周期控制基因改变 ,前者是发病基因并通过后者发挥作用。基因治疗主要有四个方面 :靶细胞选择、将目的基因导入靶细胞的基因转移方法、目的基因的? Gene therapy and surgery, chemotherapy, radiotherapy constitute the current four major cancer treatment pillars. At the molecular level, the main cause of cancer oncogene activation and tumor suppressor gene inactivation mutations, cell cycle control gene changes, the former is the pathogenesis of genes through which the latter play a role. There are four major aspects of gene therapy: target cell selection, target gene transfer into target cells, gene transfer methods, target genes?