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目前，国内外实验证实乙型肝炎病毒（ＨＢＶ）存在于许多肝外组织器官，致使ＨＢＶ在体内反复复制，病情演变复杂我们采用ＰＣＲ－原位扩增法检测慢性乙肝患者的骨髓，结果表明ＨＢＶＤＮＡ可以存在于骨髓组织中，此乃可能是慢性乙肝导致外用血细胞下降的病理基础１材料和方法
At present, domestic and foreign experiments confirmed that hepatitis B virus (HBV) exists in many extrahepatic tissues and organs, resulting in repeated replication of HBV in the body, the complexity of the evolution of the disease. PCR-in situ amplification was used to detect the bone marrow of patients with chronic hepatitis B. The results showed that HBVDNA May exist in bone marrow tissue, which may be the pathological basis of chronic hepatitis B leading to decreased blood cells 1 Materials and Methods